Email this article Long-term effect of supporting immunotherapy in a patient with metastatic small cell lung cancer
- Authors: Filimonov A.A.1, Kutakov N.M.1, Chekini D.A.1
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Affiliations:
- Clinical Hospital “Lapino” of the “Mother and Child” Group of companies
- Issue: Vol 4, No 3 (2024)
- Pages: 45-49
- Section: NEW DIRECTIONS AND ADVANCEMENTS IN TREATMENT OF ONCOLOGICAL DISEASES IN THE CURRENT AGE
- Published: 24.09.2024
- URL: https://mdonco.abvpress.ru/jour/article/view/136
- DOI: https://doi.org/10.17650/2782-3202-2024-4-3-45-49
- ID: 136
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Abstract
About 15 % of lung tumors are small cell lung cancer. Because of its extremely poor prognosis with a median overall survival of 10 months, and the long absence of new treatment options beyond the combination of platinum and etoposide (EP), the introduction of immunotherapy has been a significant development in the treatment of this disease. IMpower133 was the first phase III trial demonstrated a statistically significant increase in median overall survival in the atezolizumab group from 10.3 to 12.3 months. Our clinical case demonstrates the efficacy of an EP with atezolizumab. The patient got 6 courses of EP with atezolizumab and 29 courses of atezolizumab maintenance immunotherapy, indicating the efficacy and tolerability of this combination.
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About the authors
A. A. Filimonov
Clinical Hospital “Lapino” of the “Mother and Child” Group of companies
Author for correspondence.
Email: aleksii.f.cz@gmail.com
ORCID iD: 0000-0001-5842-244X
Aleksii Alekseevich Filimonov
143081; 111 1st Uspenskoe Shosse; Moscow region; Lapino
Russian FederationN. M. Kutakov
Clinical Hospital “Lapino” of the “Mother and Child” Group of companies
ORCID iD: 0000-0002-0103-446X
143081; 111 1st Uspenskoe Shosse; Moscow region; Lapino
Russian FederationD. A. Chekini
Clinical Hospital “Lapino” of the “Mother and Child” Group of companies
ORCID iD: 0000-0001-8581-1328
143081; 111 1st Uspenskoe Shosse; Moscow region; Lapino
Russian FederationReferences
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