Minimally invasive treatment of multiple primary tumors of the gastrointestinal tract. Clinical observation

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Abstract

   For now days we don’t have any guidelines for the treatment of synchronous and metachronous tumors of the upper and lower gastrointestinal tract. In this case report, we are talking about optimal treatment strategy in a patient with early gastric cancer, a neuroendocrine tumor of the sigmoid colon, and a locally advanced rectal cancer. The patient underwent laparoscopic gastrectomy and endoscopic excision of the early neuroendocrine tumor of the sigmoid colon. View of the local advanced rectal cancer patient underwent combined preoperative “sandwich” treatment with 2 courses of chemotherapy before a long course of chemoradiotherapy and 2 courses of chemotherapy after. The treatment was well tolerated. Ten weeks later, the patient gets surgical procedure: laparoscopic low anterior resection with loop colostomy followed by adjuvant chemotherapy. At the end of chemotherapy colostomy closure was done. The minimally invasive surgical treatment is safe and feasible in patients with synchronous malignancies of upper and lower gastrointestinal tract. Fast track rehabilitation and minimal surgical trauma ensure timely delivery of chemotherapy.

About the authors

J. M. Madyarov

Clinical Hospital “Lapino” of the “Mother and Child” Group of companies

Author for correspondence.
Email: jasur2001@mail.ru
ORCID iD: 0000-0001-9992-3822

Jasur Makhirovich Madyarov

143081

111 1st Uspenskoe Shosse

Moscow region

Lapino

Russian Federation

A. A. Filatov

Clinical Hospital “Lapino” of the “Mother and Child” Group of companies

ORCID iD: 0009-0003-0911-6405

143081

111 1st Uspenskoe Shosse

Moscow region

Lapino

Russian Federation

A. E. Kulikov

Clinical Hospital “Lapino” of the “Mother and Child” Group of companies

ORCID iD: 0000-0002-3024-9283

143081

111 1st Uspenskoe Shosse

Moscow region

Lapino

Russian Federation

Z. R. Rasulov

Clinical Hospital “Lapino” of the “Mother and Child” Group of companies

ORCID iD: 0000-0002-2306-407X

143081

111 1st Uspenskoe Shosse

Moscow region

Lapino

Russian Federation

L. A. Shestakova

Clinical Hospital “Lapino” of the “Mother and Child” Group of companies

ORCID iD: 0000-0002-5298-8124

143081

111 1st Uspenskoe Shosse

Moscow region

Lapino

Russian Federation

D. A. Chekini

Clinical Hospital “Lapino” of the “Mother and Child” Group of companies

143081

111 1st Uspenskoe Shosse

Moscow region

Lapino

Russian Federation

I. N. Iurichev

Clinical Hospital “Lapino” of the “Mother and Child” Group of companies

ORCID iD: 0000-0002-1345-041X

143081

111 1st Uspenskoe Shosse

Moscow region

Lapino

Russian Federation

V. V. Vereshchak

Clinical Hospital “Lapino” of the “Mother and Child” Group of companies

ORCID iD: 0000-0002-6850-6919

143081

111 1st Uspenskoe Shosse

Moscow region

Lapino

Russian Federation

E. N. Puchkova

Clinical Hospital “Lapino” of the “Mother and Child” Group of companies

ORCID iD: 0000-0002-7743-0549

143081

111 1st Uspenskoe Shosse

Moscow region

Lapino

Russian Federation

A. O. Rasulov

Clinical Hospital “Lapino” of the “Mother and Child” Group of companies

ORCID iD: 0000-0002-5565-615X

143081

111 1st Uspenskoe Shosse

Moscow region

Lapino

Russian Federation

R. A. Rasulov

I. M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)

ORCID iD: 0000-0002-7804-5335

119991

Bld. 2, 8 Trubetskaya St.

Moscow

Russian Federation

References

  1. Lee S.C., Nam K., Nam D. et al. Early gastric cancer with three gastric gastrointestinal stromal tumors combined with synchronous colon cancer: a case report. World J Surg Oncol 2020;18(1):231. doi: 10.1186/s12957-020-02013-4
  2. Eom B.W., Lee H.J., Yoo M.W. et al. Synchronous and metachronous cancers in patients with gastric cancer. J Surg Oncol 2008;98(2):106–10. doi: 10.1002/jso.21027
  3. Lee J.H., Bae J.S., Ryu K.W. et al. Gastric cancer patients at high-risk of having synchronous cancer. World J Gastroenterol 2006;12(16):2588–92. doi: 10.3748/wjg.v12.i16.2588
  4. Saito S., Hosoya Y., Togashi K. et al. Prevalence of synchronous colorectal neoplasms detected by colonoscopy in patients with gastric cancer. Surg Today 2008;38(1):20–5. doi: 10.1007/s00595-007-3567-8
  5. Van der Pas M.H., Haglind E., Cuesta M.A. et al. Laparoscopic versus open surgery for rectal cancer (COLOR II): short-term outcomes of a randomised, phase 3 trial. Lancet Oncol 2013;14(3):210–8. doi: 10.1016/S1470-2045(13)70016-0
  6. Ojima T., Nakamori M., Nakamura M. et al. Laparoscopic combined resection of synchronous gastric and colorectal cancer. Surg Laparosc Endosc Percutan Tech 2015;25(1):43–6. doi: 10.1097/SLE.0b013e3182a2f0f5
  7. Lee S.H., Ahn B.K., Baek S.U. Simultaneous laparoscopy-assisted resection for synchronous colorectal and gastric cancer. Kosin Med J 2015;30(2):115–21. doi: 10.7180/kmj.2015.30.2.115
  8. Tokunaga M., Hiki N., Fukunaga T. et al. Laparoscopic surgery for synchronous gastric and colorectal cancer: a preliminary experience. Langenbecks Arch Surg 2010;395(3):207–10. doi: 10.1007/s00423-009-0514-8
  9. Goksoy B. Simultaneous totally laparoscopic distal gastrectomy and anterior resection for synchronous gastric and colon cancer. Cureus 2021;13(6):e15692. doi: 10.7759/cureus.15692
  10. Yajima K., Kosugi S., Kano Y. et al. Two-step laparoscopic surgery for a patient with synchronous double cancer of the colon and stomach accompanied by severe chronic obstructive pulmonary disease. Case Rep Surg 2013;2013:246515. doi: 10.1155/2013/246515

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