Treatment of patients with multiple primary malignant neoplasms (solid tumors and malignant diseases of the hematopoietic tissue) using systems for independent prolonged infusion therapy. Clinical observations

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Abstract

Study of the problem of multiple primary malignant neoplasms (MPMNs) becomes more important and significant in modern clinical oncology. MPMN is a varied group of independent tumors of varying origin located in one or several organs. Due to introduction of single-use elastomeric microinfusion pumps into the clinical practice, continuous cyclical drug outpatient and in-hospital treatment of oncological patients with MPMNs can be performed. Significant successes of specific therapy led to increased lifespan of patients with MPMNs. Prolonged administration of drugs using infusion pump with set velocity allows to deliver cytostatics into the patient’s body in strictly controlled amounts. The article presents 2 clinical cases of effective antitumor treatment of patients with MPMNs using infusion pum

About the authors

D. A. Chekini

Clinical Hospital “Lapino” of the “Mother and Child” Group of companie

Author for correspondence.
Email: d.chekini@mcclinics.ru
ORCID iD: 0000-0001-8581-1328

111 1st Uspenskoe Shosse, Lapino, Moscow region 143081

Russian Federation

N. M. Kutakov

Clinical Hospital “Lapino” of the “Mother and Child” Group of companie

ORCID iD: 0000-0002-0103-446X

111 1st Uspenskoe Shosse, Lapino, Moscow region 143081

Russian Federation

T. A. Sen’kina

MGIMO-MED Medical University

3 Novosportivnaya St., Odintsovo, Moscow region 143007

Russian Federation

P. A. Zeynalova

Clinical Hospital “Lapino” of the “Mother and Child” Group of companie; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University

ORCID iD: 0000-0003-1564-424X

111 1st Uspenskoe Shosse, Lapino, Moscow region 143081

Bld. 2, 8 Trubetskaya St., Moscow 119991

Russian Federation

References

  1. Miller K.D., Nogueira L., Mariotto A.B. et al. Cancer treatment and survivorship statistics, 2019. CA Cancer J Clin 2019;69(5):363–85. doi: 10.3322/caac.21565
  2. Coyte A., Morrison D.S., McLoone P. Second primary cancer risk – the impact of applying different definitions of multiple primaries: results from a retrospective population-based cancer registry study. BMC Сancer 2014;14:272. doi: 10.1186/1471-2407-14-272
  3. Cianfriglia F., Di Gregorio D.A., Manieri A. Multiple primary tumours in patients with oral squamous cell carcinoma. Oral Oncol 1999;35(2):157–63. doi: 10.1016/s1368-8375(98)00105-5
  4. International classification of diseases for oncology (ICD-O). 3rd edn., 1st revision. Ed. by A. Fritz, C. Percy, A. Jack et al. WHO, 2013. 252 p.
  5. A review of the definition for multiple primary cancers in the United States. Workshop proceedings from December 4–6, 2002, in Princeton, New Jersey. Ed. by H.L. Howe. Springfield (IL): North American Association of Central Cancer Registries, 2003. 40 p.
  6. Stepanova Yu.A., Kalinin D.V., Vishnevsky V.A. Primary multiple malignant tumors (literature review). Meditsinskaya vizualizatsia = Medical Imaging 2015;(6):93–102. Available at: https://medvis.vidar.ru/jour/article/download/167/168
  7. Agabekyan G.O., Kropotov M.A., Saprina O.A. et al. Second primary cancer in patients with head and neck squamous cell carcinoma (review of the literature). Sovremennaya onkologiya = Journal of Modern Oncology 2014;16(2):82–6. (In Russ.).
  8. ICU Medical large volume infusion pump. Available at: https://www.icumed.com/products/infusion-therapy/infusionpumps-and-software/plum-large-volume-pumps/plum-360/.
  9. Baxter Healthcare Corporation. Operator’s Manual SIGMA Spectrum Infusion Pump with Master Drug Library 35700BAX2 Pump Operating Software Version 8.00 for use with Master Drug Library Version 8 ii Manual 41018v0800 SIGMA Spectrum Infusion System Revision M Operator’s Manual iii SIGMA Sp. Available at: www.sigmapumps.com (2018, 21.12.2020).
  10. Chen H., Pan T., He Y. et al. Primary mediastinal B-cell lymphoma: novel precision therapies and future directions. Front Oncol 2021;11:654854. doi: 10.3389/fonc.2021.654854
  11. Ryabukhina Yu.E., Zeynalova P.A., Gruzdev V.E. et al. Safe drug therapy in clinical practice: experience of using microinfusion singleuse mechanical systems in treatment of patients with malignant diseases of hematopoietic tissue and solid tumors. MD-Onco 2022; 2(2):51–62. (In Russ.). doi: 10.17650/2782-3202-2022-2-2-51-62
  12. Isyangulova A.Z., Shin A.R., Petkau V.V. Central venous access. Practical recommendations of RUSSCO, part 2. Zlokachestvenniye opukholy = Malignant tumors 2023;13(3s2):280–91. doi: 10.18027/2224-5057-2023-13-3s2-2-280-291
  13. Skryabina E.A., Dunn T.S. Disposable infusion pumps. Am J Health Syst Pharm 2006;63(13):1260–8. doi: 10.2146/ajhp050408

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