MD-OncoMD-OncoMD-Onco2782-32022782-6171Publishing House ABV Press14210.17650/2782-3202-2024-4-3-86-92RARE AND COMPLEX CLINICAL SITUATIONS: DIAGNOSIS AND SELECTION OF TREATMENT TACTICSРЕДКИЕ И СЛОЖНЫЕ КЛИНИЧЕСКИЕ СИТУАЦИИ: ДИАГНОСТИКА И ВЫБОР ТАКТИКИ ЛЕЧЕНИЯTransesophageal endoscopic ultrasound-guided aspiration of mediastinal lymph node. Clinical caseТонкоигольная чреспищеводная пункция лимфатического узла средостения под контролем эндоскопической ультрасонографии. Клинический случайhttps://orcid.org/0000-0002-1345-041XIurichevI. N.ЮричевИ. Н.
Russian Federation

Ilia Nikolaevich Iurichev

143081; 111 1st Uspenskoe Shosse; Moscow region; Lapino 

Илья Николаевич Юричев

143081; 1-е Успенское шоссе, 111; Московская обл.; д. Лапино

ilia-yurichev@yandex.ruhttps://orcid.org/0000-0002-6850-6919VereshchakV. V.ВерещакВ. В.
Russian Federation

143081; 111 1st Uspenskoe Shosse; Moscow region; Lapino 

143081; 1-е Успенское шоссе, 111; Московская обл.; д. Лапино

Clinical Hospital “Lapino” of the “Mother and Child” Group of companiesКлинический госпиталь «Лапино» группы компаний «Мать и Дитя»250920244386922409202424092024Copyright ©; 2024, ABV-PressCopyright ©; 2024, АБВ-пресс2024ABV-PressАБВ-прессhttps://mdonco.abvpress.ru/jour/about/editorialPolicieshttps://mdonco.abvpress.ru/jour/article/view/142

   In oncologic practice, metastatic lesions in the mediastinal lymph nodes are primarily associated with lung cancer because of its high morbidity. However, lesions in mediastinal lymph nodes are quite common in the context of various other benign and malignant processes. Therefore, due to the anatomy of this zone, difficulties of visualization of specific lymph node groups, complicated differential diagnosis of benign and malignant processes, the problem of sampling biological materials from the affected area remains important and unsolved. Transesophageal endoscopic ultrasound-guided aspiration is a highly effective and safe method of diagnosis and staging of oncologic diseases associated with metastatic lesions in the mediastinal lymph nodes.

   Метастатическое поражение лимфатических узлов средостения в онкологической практике прежде всего ассоциируется с раком легкого. Это связано с повсеместно высоким уровнем заболеваемости, однако поражение лимфатических узлов средостения при других различных доброкачественных и злокачественных процессах также широко распространено. В связи с особенностями анатомии данной зоны, трудностью визуализации отдельных групп лимфатических узлов, сложностью дифференциальной диагностики злокачественного и доброкачественного процессов проблема получения биологического материала из пораженного очага остается актуальной и нерешенной. Чреспищеводная тонкоигольная пункция под контролем эндоскопической ультрасонографии является высокоэффективным и безопасным методом диагностики и стадирования онкологических заболеваний, связанных с метастатическим поражением лимфатических узлов средостения.

metastatic lesions in mediastinal lymph nodeslung cancertransesophageal endoscopic ultrasound-guided aspirationметастатическое поражение лимфатических узлов средостениярак легкогочреспищеводная тонкоигольная пункция под контролем эндоскопической ультрасонографииThe work was performed without external fundingРабота выполнена без спонсорской поддержкиSilvestri G.A., Gonzalez A.V., Jantz M.A. et al. Methods for staging nonsmall cell lung cancer. Diagnosis and management of lung cancer, 3rd edn. American College of Chest Physicians evidence-based clinical practice guidelines. Chest 2013;143 (Suppl):211s–50s. DOI: 10.1378/chest.12-2355Van Vliet E.P., Eijkemans M.J., Poley J.W. et al. Staging of esophageal carcinoma in low-volume EUS center compared with reported results from high-volume centers. Gastrointestinal Endosc 2006;63(7):938–47. DOI: 10.1016/j.gie.2006.01.053Detterbeck F.C., Jantz M.A., Wallace M. et al. Invasive mediastinal staging of lung cancer: ACCP evidence-based clinical practice guidelines (2nd edn.). Chest 2007;132(3 suppl):202S–20S. DOI: 10.1378/chest.07-1362Sharples L.D., Jackson C., Wheaton E. et al. Clinical effectiveness and cost-effectiveness of endobronchial and endoscopic ultrasound relative to surgical staging in potentially resectable lung cancer: results from the ASTER randomised controlled trial. Health Technol Assess 2012;16(18):1–75.Navani N., Brown J.M., Nankivell M. et al. Suitability of endobronchial ultrasound-guided transbronchial needle aspiration specimens for subtyping and genotyping of non-small cell lung cancer: a multicenter study of 774 patients. Am J Respir Crit Care Med 2012;185(12):1316–22. DOI: 10.1164/rccm.201202-0294OCMountain C.F., Dresler C.M. Regional lymph node classification for lung cancer staging. Chest 1997;111(6):1718–23. DOI: 10.1378/chest.111.6.1718Annema J.T., Rabe K.F. EUS and EBUS in non-small cell lung cancer endosonography. In: Endosonography. Ed. by R.H. Hawes. 2nd edn. Philadelphia, PA: Elsevier, 2011.Catalano M.F., Sivak M.V. Jr., Rice J.T. et al. Endosonographic features predictive of lymph nodes metastasis. Gastrointest Endosc 1994;40(4):442–6. DOI: 10.1016/s0016-5107(94)70206-3Săftoiu A., Vilmann Р., Ciurea Т. et al. Dynamic analysis of EUS used for the differentiation of benign and malignant lymph nodes. Gastrointest Endosc 2007;66(2):291–300. DOI: 10.1016/j.gie.2006.12.039Yasuda I., Tsurumi H., Omar S. et al. Endoscopic ultrasound-guided fine-needle aspiration biopsy for lymphadenopathy of unknown origin. Endoscopy 2006;38(9):919–24. DOI: 10.1055/s-2006-944665Labarca G., Aravena C., Ortega F. Minimally invasive methods for staging in lung cancer : systematic review and meta-analysis. Pulm Med 2016;2016:1024709. DOI: 10.1155/2016/1024709Diehl D.L., Cheruvattath R., Facktor M.A., Go B.D. Infection after endoscopic ultrasound-guided aspiration of mediastinal cysts. Interact Cardiovasc Thorac Surg 2010;10(2):338–40. DOI: 10.1510/icvts.2009.217067Varadarajulu S., Fraig M., Schmulewitz N. et al. Comparison of EUS-guided 19-gauge Tru-cut needle biopsy with EUS-guided fine-needle aspiration. Endoscopy 2004;36(5):397–401. DOI: 10.1055/s-2004-814316Westerterp M., van den Berg J.G., van Lanschot J.J., Fockens P. Intramural bronchogenic cysts mimicking solid tumors. Endoscopy 2004;36(12):1119–22. DOI: 10.1055/s-2004-826042Burdyukov M.S., Nechipay A.M., Yurichev I.N. et al. Adverse events associated with endoscopic ultrasonography with fine-needle aspiration (retrospective study). Povolzhskiy onkologicheskiy vestnik = Volga Oncological Bulletin 2016;2(24):87–100. (In Russ.).Бурдюков М.С., Нечипай А.М., Юричев И.Н. и др. Осложнения эндоскопической ультрасонографии и тонкоигольной пункции под контролем эндосонографии (клинический опыт использования методики). Поволжский онкологический вестник 2016;2(24):87–100.Will U., Meyer F., Bosseckert H. Successful endoscopic management of iatrogenic mediastinal infection and subsequent esophagomediastinal fistula, following endosonographically guided fine-needle aspiration biopsy. Endoscopy 2005;37(1):88–90. DOI: 10.1055/s-2004-826085Dоi S., Yasuda I., Iwashita T. et al. Needle tract implantation on the esophageal wall after EUS-guided FNA of metastatic mediastinal lymphadenopathy. Gastrointest Endosc 2008;67:988–90. DOI: 10.1016/j.gie.2007.10.025Paquin S.C., Gariépy G., Lepanto L. et al. A first report of tumor seeding because of EUS-guided FNA of a pancreatic adenocarcinoma. Gastrointest Endosc 2005;61(4):610–1. DOI: 10.1016/s0016-5107(05)00082-9Shah J.N., Fraker D., Guerry D. et al. Melanoma seeding of an EUS-guided fine needle track. Gastrointest Endosc 2004;59(7):923–4. DOI: 10.1016/s0016-5107(04)00340-2Levy M.J., Gleeson F.C., Campion M.B. et al. Prospective cytological assessment of gastrointestinal luminal fluid acquired during EUS: a potential source of false-positive FNA and needle tract seeding. Am J Gastroenterol 2010;105(6):1311–8. DOI: 10.1038/ajg.2010.80Vilmann P., Krasnik M., Larsen S.S. et al. Transesophageal endoscopic ultrasoundguided fine-needle aspiration (EUS-FNA) and endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) biopsy: a combined approach in the evaluation of mediastinal lesions. Endoscopy 2005;37(9): 833–9. DOI: 10.1055/s-2005-870276Wallace M.B., Pascual J.M.S., Raimondo M. et al. Minimally invasive endoscopic staging of suspected lung cancer. JAMA 2008;299(5):540–6. DOI: 10.1001/jama.299.5.540Annema J.T., Van Meerbeeck J.P., Rintoul R.C. et al. Mediastinoscopy vs endosonography for mediastinal nodal staging of lung cancer: a randomized trial. JAMA 2010;304(20):2245–52. DOI: 10.1001/jama.2010.1705Herth F. J. F., Krasnik M., Kahn N. et al. Combined endoscopic-endobronchial ultrasoundguided fine-needle aspiration of mediastinal lymph nodes through a single bronchoscope in 150 patients with suspected lung cancer. Chest 2010;138(4):790–4. DOI: 10.1378/chest.09-2149Hwangbo B., Lee G.K., Lee H.S. et al. Transbronchial and transesophageal fine-needle aspiration using an ultrasound bronchoscope in mediastinal staging of potentially operable lung cancer. Chest 2010;138(4):795–802. DOI: 10.1378/chest.09-2100Szlubowski A., Soja J., Kocoń P. et al. A comparison of the combined ultrasound of the mediastinum by use of a single ultrasound bronchoscope versus ultrasound bronchoscope plus ultrasound gastroscope in lung cancer staging: a prospective trial. Interac Cardiovasc Thorac Surg 2012;15(3):442–6; discussion 446. DOI: 10.1093/icvts/ivs161Ohnishi R., Yasuda I., Kato T. et al. Combined endobronchial and endoscopic ultrasound-guided fine needle aspiration for mediastinal nodal staging of lung cancer. Endoscopy 2011;43(12):1082–9. DOI: 10.1055/s-0030-1256766Kang H.J., Hwangbo B., Lee G.K. et al. EBUS-centred versus EUS-centred mediastinal staging in lung cancer: a randomized controlled trial. Thorax 2014;69(3):261–8. DOI: 10.1136/thoraxjnl-2013-203881Lee K.J., Suh G.Y., Chung M.P. et al. Combined endobronchial and transesophageal approach of an ultrasound bronchoscope for mediastinal staging of lung cancer. PLoS One 2014;9(3):e91893. DOI: 10.1371/journal.pone.0091893Liberman M., Sampalis J., Duranceau A. et al. Endosonographic mediastinal lymph node staging of lung cancer. Chest 2014;146(2):389–97. DOI: 10.1378/chest.13-2349Oki M., Saka H., Ando M. et al. Endoscopic ultrasound-guided fine needle aspiration and endobronchial ultrasound-guided transbronchial needle aspiration: are two better than one in mediastinal staging of non-small cell lung cancer? J Thorac Cardiovasc Surg 2014;148(4):1169–77. DOI: 10.1016/j.jtcvs.2014.05.023