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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">MD-Onco</journal-id><journal-title-group><journal-title xml:lang="en">MD-Onco</journal-title><trans-title-group xml:lang="ru"><trans-title>MD-Onco</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2782-3202</issn><issn publication-format="electronic">2782-6171</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">185</article-id><article-id pub-id-type="doi">10.17650/2782-3202-2025-5-2-35-44</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>SUPPORTING THERAPY ASPECTS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>АСПЕКТЫ ПОДДЕРЖИВАЮЩЕЙ ТЕРАПИИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">The current understanding of lymphedema. Literature review</article-title><trans-title-group xml:lang="ru"><trans-title>Современное представление о лимфедеме. Обзор литературы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3452-1560</contrib-id><name-alternatives><name xml:lang="en"><surname>Klyut</surname><given-names>A. S.</given-names></name><name xml:lang="ru"><surname>Клют</surname><given-names>А. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><bold>Artem Sergeyevich Klyut</bold><italic> </italic></p><p><italic>4a Vysotnaya St., Podolsk, Moscow region 142114</italic></p></bio><bio xml:lang="ru"><p><bold>Артем Сергеевич Клют</bold><italic> </italic></p><p><italic>142114 Московская область, Подольск, ул. Высотная, 4а</italic></p></bio><email>arteom.klyut@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7882-1317</contrib-id><name-alternatives><name xml:lang="en"><surname>Sergeenko</surname><given-names>E. Yu.</given-names></name><name xml:lang="ru"><surname>Сергеенко</surname><given-names>Е. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>1 Ostrovityanova St., Moscow 117997</italic></p></bio><bio xml:lang="ru"><p><italic>117997 Москва, ул. Островитянова, 1</italic></p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7574-335X</contrib-id><name-alternatives><name xml:lang="en"><surname>Kharbediya</surname><given-names>V. Kh.</given-names></name><name xml:lang="ru"><surname>Харбедия</surname><given-names>В. Х.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>4a Vysotnaya St., Podolsk, Moscow region 142114</italic></p></bio><bio xml:lang="ru"><p><italic>142114 Московская область, Подольск, ул. Высотная, 4а</italic></p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0168-8671</contrib-id><name-alternatives><name xml:lang="en"><surname>Narbutov</surname><given-names>A. G.</given-names></name><name xml:lang="ru"><surname>Нарбутов</surname><given-names>А. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>117 Leninskiy Ave., Moscow 119571</italic></p></bio><bio xml:lang="ru"><p><italic>119571 Москва, Ленинский пр-кт, 117</italic></p></bio><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2397-3484</contrib-id><name-alternatives><name xml:lang="en"><surname>Glazyrina</surname><given-names>A. A.</given-names></name><name xml:lang="ru"><surname>Глазырина</surname><given-names>А. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>4a Vysotnaya St., Podolsk, Moscow region 142114</italic></p></bio><bio xml:lang="ru"><p><italic>142114 Московская область, Подольск, ул. Высотная, 4а</italic></p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8520-2378</contrib-id><name-alternatives><name xml:lang="en"><surname>Petryaykina</surname><given-names>E. E.</given-names></name><name xml:lang="ru"><surname>Петряйкина</surname><given-names>Е. Е.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>117 Leninskiy Ave., Moscow 119571</italic></p></bio><bio xml:lang="ru"><p><italic>119571 Москва, Ленинский пр-кт, 117</italic></p></bio><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Federal Children’s Rehabilitation Center “Korablik” – structural division of the Russian Children’s Clinical Hospital – branch of the N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">Федеральный детский реабилитационный центр «Кораблик» – структурное подразделение Российской детской клинической больницы – филиала ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Russian Children’s Clinical Hospital – branch of the N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">Российская детская клиническая больница – филиал ФГАОУ ВО «Российский национальный</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2025-05-18" publication-format="electronic"><day>18</day><month>05</month><year>2025</year></pub-date><volume>5</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>35</fpage><lpage>44</lpage><history><date date-type="received" iso-8601-date="2025-05-18"><day>18</day><month>05</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-05-18"><day>18</day><month>05</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, ABV-Press</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, АБВ-пресс</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">ABV-Press</copyright-holder><copyright-holder xml:lang="ru">АБВ-пресс</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://mdonco.abvpress.ru/jour/about/editorialPolicies</ali:license_ref></license></permissions><self-uri xlink:href="https://mdonco.abvpress.ru/jour/article/view/185">https://mdonco.abvpress.ru/jour/article/view/185</self-uri><abstract xml:lang="en"><p>Lymphedema is a chronic, long-lasting and usually sluggish disease, which leads to partial or complete impairment of limb function, limits the patient’s social opportunities. This article presents a review of the medical literature on the modern concept of lymphedema, its classification, etiology, diagnosis and treatment.</p></abstract><trans-abstract xml:lang="ru"><p>Лимфедема является хроническим, длительно и, как правило, вялотекущим заболеванием, которое приводит к частичному или полному нарушению функции конечности, вследствие чего происходит ограничение возможностей пациента в быту и социальной среде. В статье представлена информация о классификации, этиологии, диагностике лимфедемы, лечении и реабилитации больных с данным заболеванием.</p></trans-abstract><kwd-group xml:lang="en"><kwd>lymphedema</kwd><kwd>rehabilitation</kwd><kwd>physical therapy</kwd><kwd>edema</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>лимфедема</kwd><kwd>реабилитация</kwd><kwd>лечебная физическая культура</kwd><kwd>отек</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Vignes S., Albuisson J., Champion L. et al. Primary lymphedema French National Diagnosis and Care Protocol (PNDS; Protocole National de Diagnostic et de Soins). Orphanet J Rare Dis 2021;16(1):18. DOI: 10.1186/s13023-020-01652-w</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Ogino R., Yokooji T., Hayashida M. et al. Emerging antiinflammatory pharmacotherapy and cell-based therapy for lymphedema. Int J Mol Sci 2022;23(14):7614. 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