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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">MD-Onco</journal-id><journal-title-group><journal-title xml:lang="en">MD-Onco</journal-title><trans-title-group xml:lang="ru"><trans-title>MD-Onco</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2782-3202</issn><issn publication-format="electronic">2782-6171</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">198</article-id><article-id pub-id-type="doi">10.17650/2782-3202-2025-5-3-58-70</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>NEW DIRECTIONS AND ADVANCEMENTS IN TREATMENT OF ONCOLOGICAL DISEASES IN THE CURRENT AGE</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>НОВЫЕ НАПРАВЛЕНИЯ И УСПЕХИ В ЛЕЧЕНИИ ОНКОЛОГИЧЕСКИХ ЗАБОЛЕВАНИЙ НА СОВРЕМЕННОМ ЭТАПЕ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Analysis of factors and errors affecting the development of complications after breast reconstruction with silicone implants in cancer patients</article-title><trans-title-group xml:lang="ru"><trans-title>Анализ факторов и ошибок, влияющих на развитие осложнений после реконструкции молочной железы силиконовыми эндопротезами у онкологических пациенток</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Troshenkov</surname><given-names>E. A.</given-names></name><name xml:lang="ru"><surname>Трошенков</surname><given-names>Е. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2nd Botkinsky proezd, Moscow 125284</p></bio><bio xml:lang="ru"><p>125284 Москва, 2-й Боткинский проезд, 3</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Vlasova</surname><given-names>M. Yu.</given-names></name><name xml:lang="ru"><surname>Власова</surname><given-names>М. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2nd Botkinsky proezd, Moscow 125284</p></bio><bio xml:lang="ru"><p>125284 Москва, 2-й Боткинский проезд, 3</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Zikiryakhodjaev</surname><given-names>A. D.</given-names></name><name xml:lang="ru"><surname>Зикиряходжаев</surname><given-names>А. Д.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2nd Botkinsky proezd, Moscow 125284</p><p>Bld. 2, 8 Trubetskaya St., Moscow 119991</p><p>6 Miklukho-Maklaya St., Moscow 117198</p></bio><bio xml:lang="ru"><p>125284 Москва, 2-й Боткинский проезд, 3</p><p>119048 Москва, ул. Трубецкая, 8, стр. 2</p><p>117198 Москва, ул. Миклухо-Маклая, 6</p></bio><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kaprin</surname><given-names>A. D.</given-names></name><name xml:lang="ru"><surname>Каприн</surname><given-names>А. Д.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2nd Botkinsky proezd, Moscow 125284</p><p>Bld. 2, 8 Trubetskaya St., Moscow 119991</p><p>6 Miklukho-Maklaya St., Moscow 117198</p><p>4 Koroleva St., Obninsk 249036</p></bio><bio xml:lang="ru"><p>125284 Москва, 2-й Боткинский проезд, 3</p><p>119048 Москва, ул. Трубецкая, 8, стр. 2</p><p>117198 Москва, ул. Миклухо-Маклая, 6</p><p>249036 Обнинск, ул. Королева, 4</p></bio><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/><xref ref-type="aff" rid="aff4"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Malik</surname><given-names>D. S.</given-names></name><name xml:lang="ru"><surname>Малик</surname><given-names>Д. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>4 Koroleva St., Obninsk 249036</p></bio><bio xml:lang="ru"><p>249036 Обнинск, ул. Королева, 4</p></bio><xref ref-type="aff" rid="aff4"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Usov</surname><given-names>F. N.</given-names></name><name xml:lang="ru"><surname>Усов</surname><given-names>Ф. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2nd Botkinsky proezd, Moscow 125284</p></bio><bio xml:lang="ru"><p>125284 Москва, 2-й Боткинский проезд, 3</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">P.A. Herzen Moscow Research Institute of Oncology – branch of the National Medical Research Center of Radiology, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">Московский научно-исследовательский онкологический институт им. П.А. Герцена – филиал ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России (Сеченовский университет)</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Peoples’ Friendship University of Russia n. a. Patrice Lumumba</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО «Российский Университет дружбы народов им. Патриса Лумумбы»</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">A.F. Tsyb Medical Radiology Research Center – branch of the National Medical Research Radiology Center, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">Медицинский радиологический научный центр им. А.Ф. Цыба – филиал ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2025-09-21" publication-format="electronic"><day>21</day><month>09</month><year>2025</year></pub-date><volume>5</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>58</fpage><lpage>70</lpage><history><date date-type="received" iso-8601-date="2025-09-19"><day>19</day><month>09</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-09-19"><day>19</day><month>09</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, ABV-Press</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, АБВ-пресс</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">ABV-Press</copyright-holder><copyright-holder xml:lang="ru">АБВ-пресс</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://mdonco.abvpress.ru/jour/about/editorialPolicies</ali:license_ref></license></permissions><self-uri xlink:href="https://mdonco.abvpress.ru/jour/article/view/198">https://mdonco.abvpress.ru/jour/article/view/198</self-uri><abstract xml:lang="en"><p>Currently, breast reconstruction with silicone endoprostheses has become widespread. This was facilitated by the simplicity of the surgical technique, rapid recovery of patients, and the availability of high-quality synthetic and biological materials. With one-stage breast reconstruction, optimal aesthetic results can be achieved in one surgical intervention. However, some factors can make adjustments to the reconstruction result. Most foreign and Russian publications are devoted to the effect of radiation therapy on the development of complications after the use of silicone endoprostheses/tissue expanders. In our article, we analyzed studies devoted to the analysis of the influence of various factors that can provoke the development of infection, implant protrusion, and other complications. Taking into account all possible criteria at the preoperative, postoperative stages, and directly during surgery, it is possible to significantly reduce the risks of implant loss and reoperations.</p></abstract><trans-abstract xml:lang="ru"><p>В настоящее время реконструкция молочной железы силиконовыми эндопротезами получила широкое распространение. Этому способствовали простота техники операции, быстрое восстановление пациентов, доступность качественных синтетических и биологических материалов. При одномоментной реконструкции молочной железы можно добиться оптимальных эстетических результатов за одно хирургическое вмешательство. Однако некоторые факторы могут привести к осложнениям и неудачному исходу реконструкции. Большинство зарубежных и российских публикаций посвящены влиянию лучевой терапии на развитие осложнений после использования силиконовых эндопротезов/тканевых экспандеров. Мы проанализировали исследования, изучающие влияние различных факторов, которые могут спровоцировать развитие инфицирования, протрузии имплантата и других осложнений. Учитывая все возможные критерии на дооперационном, послеоперационном этапах и непосредственно во время хирургического вмешательства, можно значительно снизить риски потери имплантата и реопераций.</p></trans-abstract><kwd-group xml:lang="en"><kwd>breast cancer</kwd><kwd>breast reconstruction</kwd><kwd>silicone endoprosthesis</kwd><kwd>implant</kwd><kwd>alloreconstruction</kwd><kwd>capsular contracture</kwd><kwd>radiation therapy</kwd><kwd>complication after breast reconstruction with silicone endoprosthesis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак молочной железы</kwd><kwd>реконструкция молочной железы</kwd><kwd>силиконовый эндопротез</kwd><kwd>имплантат</kwd><kwd>аллореконструкция</kwd><kwd>капсулярная контрактура</kwd><kwd>лучевая терапия</kwd><kwd>осложнение после реконструкции молочной железы силиконовым эндопротезом</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Statistics from the American Society of Plastic Surgeons. 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